I recently worked at a hospital, who had these pens in their pharmacy and medical units. These pens were so good for patient labels because they do not smear. You do have to let the ink dry for a couple of seconds before you touch it but after it’s dry, there’s no smear whatsoever. These work, especially good for left-handed people. I immediately went on Amazon and found the pink ones. The smallest box that I could buy was a 200 count and that will last me quite a long time for now. I took these to my work and have been using them for the last couple of months, and they seem to hold up fairly well. The ends tend to get stained with ink if you leave them in your pocket upside down, but other than that, they have worked very well and have not gotten Ink everywhere or exploded or been Messy . I would highly recommend for those working in clinic or hospital who need to write stuff on patient labels.